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NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients With Tumors Harboring Actionable NTRK Fusions

Trial Profile

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of LOXO-101 (Larotrectinib) in Patients With Tumors Harboring Actionable NTRK Fusions

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Dec 2019

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At a glance

  • Drugs Larotrectinib (Primary) ; Larotrectinib (Primary)
  • Indications CNS cancer; Ependymoma; Ewing's sarcoma; Germ cell and embryonal neoplasms; Glioma; Langerhans cell histiocytosis; Medulloblastoma; Neuroblastoma; Non-Hodgkin's lymphoma; Osteosarcoma; Rhabdoid tumour; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
  • Focus Therapeutic Use
  • Acronyms Pediatric MATCH
  • Most Recent Events

    • 09 Apr 2018 Planned End Date changed from 31 Mar 2022 to 30 Sep 2024.
    • 09 Apr 2018 Planned primary completion date changed from 31 Mar 2022 to 30 Sep 2024.
    • 27 Jul 2017 Status changed from not yet recruiting to recruiting.
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