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NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol

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Trial Profile

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Jan 2025

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At a glance

  • Drugs Ensartinib (Primary) ; Erdafitinib (Primary) ; Larotrectinib (Primary) ; Larotrectinib (Primary) ; Olaparib (Primary) ; Palbociclib (Primary) ; Samotolisib (Primary) ; Selpercatinib (Primary) ; Selumetinib (Primary) ; Tazemetostat (Primary) ; Tipifarnib (Primary) ; Tipifarnib (Primary) ; Ulixertinib (Primary) ; Vemurafenib (Primary)
  • Indications CNS cancer; Ependymoma; Ewing's sarcoma; Germ cell and embryonal neoplasms; Germ cell cancer; Glioma; Hepatoblastoma; Langerhans cell histiocytosis; Lymphoma; Neuroblastoma; Non-Hodgkin's lymphoma; Osteosarcoma; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
  • Focus Therapeutic Use
  • Acronyms Pediatric MATCH

    • Most Recent Events

    • 08 Jan 2025 Planned End Date changed from 30 Sep 2027 to 30 Jun 2025.
    • 08 Jan 2025 Planned primary completion date changed from 30 Sep 2027 to 30 Jun 2025.
    • 27 Dec 2024 Status changed from recruiting to active, no longer recruiting.

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