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NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol

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Trial Profile

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Sep 2024

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At a glance

  • Drugs Ensartinib (Primary) ; Erdafitinib (Primary) ; Larotrectinib (Primary) ; Larotrectinib (Primary) ; Olaparib (Primary) ; Palbociclib (Primary) ; Samotolisib (Primary) ; Selpercatinib (Primary) ; Selumetinib (Primary) ; Tazemetostat (Primary) ; Tipifarnib (Primary) ; Tipifarnib (Primary) ; Ulixertinib (Primary) ; Vemurafenib (Primary)
  • Indications CNS cancer; Ependymoma; Ewing's sarcoma; Germ cell and embryonal neoplasms; Germ cell cancer; Glioma; Hepatoblastoma; Langerhans cell histiocytosis; Lymphoma; Neuroblastoma; Non-Hodgkin's lymphoma; Osteosarcoma; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
  • Focus Therapeutic Use
  • Acronyms Pediatric MATCH

    • Most Recent Events

    • 06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 01 Apr 2022 Results from arm E (n=20) published in the Journal of Clinical Oncology
    • 08 Mar 2022 Status changed from suspended to recruiting.

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