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Phase 1, Open-label, Study of Voruciclib in Subjects With Relapsed and/or Refractory B Cell Malignancies or AML After Failure of Prior Standard Therapies and Voruciclib in Combination With Venetoclax in Subjects With Relapsed/Refractory AML

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Trial Profile

Phase 1, Open-label, Study of Voruciclib in Subjects With Relapsed and/or Refractory B Cell Malignancies or AML After Failure of Prior Standard Therapies and Voruciclib in Combination With Venetoclax in Subjects With Relapsed/Refractory AML

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 20 Mar 2026

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At a glance

  • Drugs Venetoclax (Primary) ; Voruciclib (Primary)
  • Indications Acute myeloid leukaemia; B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma
  • Focus Adverse reactions
  • Sponsors Lite Strategy; MEI Pharma

Most Recent Events

  • 17 Mar 2026 Status changed from completed to discontinued. Reason the study was stopped: Business reasons, not related to safety or efficacy results.
  • 10 Sep 2025 According to MEI Pharma media release, MEI Pharma has changed its name to Lite Strategy.
  • 10 Dec 2024 Status changed from recruiting to completed, According to the result presented at the 66th American Society of Hematology Annual Meeting and Exposition

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