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Phase 1, Open-label, Study of Voruciclib in Subjects With Relapsed and/or Refractory B Cell Malignancies or AML After Failure of Prior Standard Therapies and Voruciclib in Combination With Venetoclax in Subjects With Relapsed/Refractory AML

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Trial Profile

Phase 1, Open-label, Study of Voruciclib in Subjects With Relapsed and/or Refractory B Cell Malignancies or AML After Failure of Prior Standard Therapies and Voruciclib in Combination With Venetoclax in Subjects With Relapsed/Refractory AML

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Feb 2025

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At a glance

  • Drugs Venetoclax (Primary) ; Voruciclib (Primary)
  • Indications Acute myeloid leukaemia; B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma
  • Focus Adverse reactions
  • Sponsors MEI Pharma

Most Recent Events

  • 10 Dec 2024 Status changed from recruiting to completed, According to the result presented at the 66th American Society of Hematology Annual Meeting and Exposition
  • 10 Dec 2024 Results assessing safety and efficacy presented at the 66th American Society of Hematology Annual Meeting and Exposition
  • 09 May 2024 According to a MEI Pharma media release, the Company has completed patient enrollment of the dose expansion cohort and enrolling dose escalation cohorts.

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