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Molecularly-Driven Doublet Therapy for All Children With Refractory or Recurrent CNS Malignant Neoplasms and Young Adults With Refractory or Recurrent SHH Medulloblastoma

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Trial Profile

Molecularly-Driven Doublet Therapy for All Children With Refractory or Recurrent CNS Malignant Neoplasms and Young Adults With Refractory or Recurrent SHH Medulloblastoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Jun 2024

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At a glance

  • Drugs Gemcitabine (Primary) ; Ribociclib (Primary) ; Sonidegib (Primary) ; Trametinib (Primary) ; Filgrastim; Pegfilgrastim
  • Indications Anaplastic astrocytoma; Brain cancer; CNS cancer; Diffuse intrinsic pontine glioma; Ependymoma; Glioblastoma; Glioma; Medulloblastoma; Oligodendroglioma
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms SJDAWN

    • Most Recent Events

    • 30 May 2024 Status changed from active, no longer recruiting to completed.
    • 20 Mar 2024 Planned End Date changed from 1 Mar 2025 to 1 May 2024.
    • 02 Dec 2022 Status changed from recruiting to active, no longer recruiting.

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