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A Multicenter, Open-label, Phase 3 Study to Evaluate the Long-term Safety and Efficacy in Participants Who Are Currently on Treatment or in Follow-up in Studies That Include Pembrolizumab

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Trial Profile

A Multicenter, Open-label, Phase 3 Study to Evaluate the Long-term Safety and Efficacy in Participants Who Are Currently on Treatment or in Follow-up in Studies That Include Pembrolizumab

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 08 Oct 2025

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At a glance

  • Drugs Favezelimab (Primary) ; Favezelimab/pembrolizumab (Primary) ; Lenvatinib (Primary) ; Olaparib (Primary) ; Pembrolizumab (Primary) ; Antineoplastics; Antineoplastics
  • Indications Haematological malignancies; Solid tumours
  • Focus Therapeutic Use
  • Acronyms KEYNOTE-587; MK-3475-587/KEYNOTE-587
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 18 Aug 2025 Planned number of patients changed from 3500 to 3515.
  • 18 Aug 2025 Planned number of patients changed from 3500 to 3515.
  • 26 Feb 2025 Study arms increased from 9 to 15. New drugs added to the study arms. Drugs olaparib and favezelimab added newly.

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