Trial Profile

A Phase I/II Dose-Escalation and Expansion Study of the Selective PKC-β Inhibitor MS-553 in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 16 Apr 2025

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At a glance

Drugs Acalabrutinib (Primary) ; MS 553 (Primary) ; Obinutuzumab (Primary) ; Rituximab (Primary) ; Venetoclax (Primary)
Indications Chronic lymphocytic leukaemia
Focus Adverse reactions
Sponsors MingSight Pharmaceuticals

Most Recent Events

18 Jul 2024 Status changed from recruiting to discontinued.
12 Dec 2023 Results presented at the 65th American Society of Hematology Annual Meeting and Exposition
13 Mar 2023 Planned End Date changed from 25 May 2023 to 15 Jun 2024.

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