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A double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety, pharmacokinetics and efficacy of CRN00808 in patients with acromegaly that are responders to octreotide LAR or lanreotide depot (ACROBAT Evolve)

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Trial Profile

A double-blind, placebo-controlled, randomized withdrawal study to evaluate the safety, pharmacokinetics and efficacy of CRN00808 in patients with acromegaly that are responders to octreotide LAR or lanreotide depot (ACROBAT Evolve)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Paltusotine (Primary)
  • Indications Acromegaly
  • Focus Therapeutic Use
  • Acronyms ACROBAT EVOLVE
  • Sponsors Crinetics Pharmaceuticals

    • Most Recent Events

    • 02 Nov 2020 Status changed from active, no longer recruiting to completed.
    • 26 Oct 2020 According to a Crinetics Pharmaceuticals media release, the company is looking forward to meeting with the FDA to share these results and finalize the protocol for the planned Phase 3 program.
    • 26 Oct 2020 According to a Crinetics Pharmaceuticals media release, the company will hold a a conference call at 8:00 a.m. Eastern Time today to discuss these results. In addition, a Key Opinion Leader (KOL) call will be held on November 20th to discuss these results in the context of the current standard of care with clinical experts.

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