Phase 1/1b, Open-label, Dose-escalation, Dose-expansion, Parallel Assignment Study to Evaluate Safety and Clinical Activity of PBCAR0191 (azercabtagene Zapreleucel or "azer-cel") in Subjects with Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and R/r B-cell Acute Lymphoblastic Leukemia (B-ALL)
Latest Information Update: 28 Nov 2025
At a glance
- Drugs Azercabtagene zapreleucel (Primary) ; Cyclophosphamide; Fludarabine; Interleukin-2
- Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Precursor B-cell lymphoblastic leukaemia-lymphoma; Waldenstrom's macroglobulinaemia
- Focus Adverse reactions; First in man; Therapeutic Use
- Sponsors Imugene; Precision Biosciences
Most Recent Events
- 03 Nov 2025 Results presented in an Imugene media release.
- 17 Jul 2025 Results presented in an Imugene media release.
- 15 Jul 2025 Results presented in an Imugene media release.