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A Phase I Open-label Dose Escalation Trial of BI 1701963 as Monotherapy and in Combination With Trametinib in Patients With KRAS Mutated Advanced or Metastatic Solid Tumours

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A Phase I Open-label Dose Escalation Trial of BI 1701963 as Monotherapy and in Combination With Trametinib in Patients With KRAS Mutated Advanced or Metastatic Solid Tumours

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Mar 2025

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At a glance

  • Drugs BI 1701963 (Primary) ; Trametinib (Primary)
  • Indications Adenocarcinoma; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 25 Mar 2025 Planned End Date changed from 30 Apr 2025 to 31 Dec 2025.
  • 25 Mar 2025 Planned primary completion date changed from 30 Apr 2025 to 31 Dec 2025.
  • 23 Sep 2024 Planned End Date changed from 31 Oct 2025 to 30 Apr 2025.

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