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A Phase 1, Open-Label, Fixed-Sequence, Drug-Drug Interaction Study of APX001 to Evaluate the Effects of CYP3A4 Inhibition and Pan-CYP Induction in Two Parallel Groups of Healthy Male and Female Subjects

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A Phase 1, Open-Label, Fixed-Sequence, Drug-Drug Interaction Study of APX001 to Evaluate the Effects of CYP3A4 Inhibition and Pan-CYP Induction in Two Parallel Groups of Healthy Male and Female Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 May 2024

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At a glance

  • Drugs Fosmanogepix (Primary) ; Itraconazole; Manogepix; Rifampicin
  • Indications Aspergillosis; Candidaemia; Coccidioidomycosis; Mycoses
  • Focus Pharmacokinetics
  • Sponsors Amplyx Pharmaceuticals; Pfizer

    • Most Recent Events

    • 08 Jun 2020 Status changed from recruiting to completed.
    • 20 Nov 2019 New trial record

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