Trial Profile

APG-2575CU101, A Phase Ib Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents in Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 16 Apr 2025

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At a glance

Drugs Acalabrutinib (Primary) ; Lisaftoclax (Primary) ; Rituximab; Voruciclib
Indications Chronic lymphocytic leukaemia
Focus Adverse reactions
Acronyms SACRED
Sponsors Ascentage Pharma

10 Apr 2025 The protocol has been amended to change in size of arms with increase in patient population.
10 Apr 2025 Planned number of patients changed from 254 to 144.
10 Apr 2025 Planned End Date changed from 30 Jun 2026 to 30 Jun 2027.

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