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A Phase 2a Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, Pharmacokinetics, and Efficacy of Deupirfenidone (LYT-100) in Patients With Breast Cancer-Related Upper Limb Secondary Lymphoedema

Trial Profile

A Phase 2a Double-Blind, Placebo-Controlled Study to Determine the Safety, Tolerability, Pharmacokinetics, and Efficacy of Deupirfenidone (LYT-100) in Patients With Breast Cancer-Related Upper Limb Secondary Lymphoedema

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 26 Apr 2024

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At a glance

  • Drugs Deupirfenidone (Primary)
  • Indications Lymphoedema
  • Focus Adverse reactions; Pharmacokinetics; Proof of concept
  • Sponsors PureTech Health
  • Most Recent Events

    • 26 Mar 2024 The phase of this trial has been amended to phase 2 from phase 1/2, number of treatment arms reduced to 2 from 8, no longer recruiting healthy volunteers.
    • 11 Jan 2024 Status changed from completed to discontinued. (Primary objective/endpoint has been established, will not pursue development of the diseaseindication further )
    • 26 Sep 2022 Status changed from recruiting to completed.

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