Trial Profile

A Phase 1/2, Open-label, Multicenter, Dose Escalation and Dose Expansion Study of SAR442720 in Combination With Other Agents in Participants With Advanced Malignancies

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 04 Jun 2025

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At a glance

Drugs Adagrasib (Primary) ; Pembrolizumab (Primary) ; Vociprotafib (Primary)
Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
Sponsors Sanofi

Most Recent Events

29 Apr 2024 Status changed from active, no longer recruiting to discontinued as per Sponsor's decision, but not due to any safety concern.
16 Jan 2024 Planned End Date changed from 15 Jul 2024 to 29 Mar 2024.
16 Jan 2024 Planned primary completion date changed from 15 Jul 2024 to 29 Mar 2024.

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