Trial Profile

A Phase II Study of Acalabrutinib in Combination With R-CHOP Chemotherapy in Previously Untreated Mantle Cell Lymphoma

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 18 Jun 2026

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At a glance

Drugs Acalabrutinib (Primary) ; Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
Indications Mantle-cell lymphoma
Focus Therapeutic Use
Acronyms The Rectangle Trial

Most Recent Events

12 Jun 2026 Planned primary completion date changed from 1 Oct 2023 to 1 Sep 2028.
12 Jun 2026 Status changed from recruiting to active, no longer recruiting.
18 Feb 2025 Planned number of patients changed from 54 to 105.

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