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Phase II Study of Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC)

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Trial Profile

Phase II Study of Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 23 Aug 2023

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At a glance

  • Drugs Hydroxychloroquine (Primary) ; Trametinib (Primary)
  • Indications Biliary cancer; Carcinoma; Cholangiocarcinoma; Gallbladder cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 28 Jul 2023 Status changed to discontinued.
    • 11 May 2023 Status changed from recruiting to completed.
    • 09 Jul 2022 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.

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