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A Phase 2 Study of Polatuzumab Vedotin With Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for Relapsed/Refractory Diffuse Large B-cell Lymphoma

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Trial Profile

A Phase 2 Study of Polatuzumab Vedotin With Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for Relapsed/Refractory Diffuse Large B-cell Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Sep 2026

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At a glance

  • Drugs Carboplatin (Primary) ; Etoposide (Primary) ; Ifosfamide (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 11 Sep 2026 Planned End Date changed from 1 Jul 2026 to 28 Jun 2027.
  • 03 Sep 2025 Planned End Date changed from 8 Jul 2025 to 1 Jul 2026.
  • 17 Feb 2025 Planned End Date changed from 31 Dec 2024 to 8 Jul 2025.

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