Trial Profile

Phase II Study of Polatuzumab Vedotin in Combination With Chemotherapy in Subjects With Richter's Transformation

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 15 Oct 2025

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At a glance

Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Etoposide (Primary) ; Polatuzumab vedotin (Primary) ; Prednisone (Primary) ; Rituximab (Primary)
Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Richter's syndrome
Focus Therapeutic Use

Most Recent Events

07 Oct 2025 Planned End Date changed from 1 Sep 2026 to 1 Sep 2027.
07 Oct 2025 Planned primary completion date changed from 1 Sep 2025 to 1 Sep 2026.
19 Dec 2022 Planned End Date changed from 1 Jun 2024 to 1 Sep 2026.

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