A Phase II Study of BTK Inhibitor Acalabrutinib and PI3Kδ Inhibitor Umbralisib in Combination With Ublituximab (AU2) in Patients With Previously Untreated Mantle Cell Lymphoma (MCL)
Latest Information Update: 23 Jul 2026
At a glance
- Drugs Acalabrutinib (Primary) ; Ublituximab (Primary) ; Umbralisib (Primary)
- Indications Mantle-cell lymphoma
- Focus Therapeutic Use
Most Recent Events
- 17 Jul 2026 Planned End Date changed from 20 Sep 2025 to 21 Jul 2026.
- 15 Nov 2023 Planned End Date changed from 20 Sep 2023 to 20 Sep 2025.
- 28 Feb 2023 Status changed from suspended to active, no longer recruiting.