Trial Profile

Evaluation of TH104 for Moderate to Severe Pruritus in Primary Biliary Cholangitis: a Double-blind, Randomized, Placebo-controlled, Phase 2a Study

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 07 Oct 2025

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At a glance

Drugs Nalmefene (Primary)
Indications Eczema; Pruritus
Focus Adverse reactions
Sponsors Avior Bio; Tharimmune

Most Recent Events

09 Sep 2025 Planned End Date changed from 1 Apr 2026 to 1 Jun 2027.
09 Sep 2025 Planned primary completion date changed from 1 Mar 2026 to 1 Mar 2027.
09 Sep 2025 Planned initiation date changed from 1 Mar 2025 to 1 Jun 2026.

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