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An open-label study to investigate the safety and pharmacokinetics of multiple ascending doses of antisense oligonucleotide STK-001 in children and adolescents with Dravet syndrome

Trial Profile

An open-label study to investigate the safety and pharmacokinetics of multiple ascending doses of antisense oligonucleotide STK-001 in children and adolescents with Dravet syndrome

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 12 Mar 2026

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At a glance

  • Drugs Zorevunersen (Primary)
  • Indications Dravet syndrome
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms ADMIRAL; STK-001-DS-102 (ADMIRAL)
  • Sponsors Stoke Therapeutics

Most Recent Events

  • 04 Mar 2026 According to a Biogen media release, data from the trial were presented in The New England Journal of Medicine (NEJM).
  • 04 Mar 2026 Results presented in the Biogen Media Release
  • 05 Dec 2025 According to the Stoke Therapeutics media release, data from this trial were presented at the 2025 American Epilepsy Society (AES) Annual Meeting in Atlanta, Georgia.

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