Open-label, Prospective Phase III Clinical Study to Compare Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) With Rituximab, Ifosfamide, Carboplatin and Etoposide (R-ICE) Alone as Salvage Therapy in Patients With Primary Refractory or Relapsed Diffuse Large B-cell Lymphoma (DLBCL)
Latest Information Update: 18 Jun 2026
At a glance
- Drugs Carboplatin (Primary) ; Etoposide (Primary) ; Ifosfamide (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary)
- Indications B-cell lymphoma; Diffuse large B cell lymphoma; T-cell lymphoma
- Focus Therapeutic Use
- Acronyms Pola-R-ICE
Most Recent Events
- 10 Jun 2026 Status changed from active, no longer recruiting to completed.
- 30 Sep 2025 Planned End Date changed from 31 Dec 2027 to 31 Dec 2025.
- 18 Feb 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.