Trial Profile

Open-label, Prospective Phase III Clinical Study to Compare Polatuzumab Vedotin Plus Rituximab, Ifosfamide, Carboplatin and Etoposide (Pola-R-ICE) with Rituximab, Ifosfamide, Carboplatin and Etoposide (R-ICE) Alone As Salvage Therapy in Patients with Primary Refractory or Relapsed Diffuse Large B-cell Lymphoma (DLBCL)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 24 Feb 2025

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At a glance

Drugs Carboplatin (Primary) ; Etoposide (Primary) ; Ifosfamide (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary)
Indications B-cell lymphoma; Diffuse large B cell lymphoma; T-cell lymphoma
Focus Therapeutic Use
Acronyms Pola-R-ICE

18 Feb 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.
18 Feb 2025 Planned primary completion date changed from 31 Oct 2024 to 31 Dec 2026.
18 Feb 2025 Status changed from recruiting to active, no longer recruiting.

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