Trial Profile

A Phase 1/2 Study of Acalabrutinib, Venetoclax, and Obinutuzumab in Patients with Relapsed/refractory and Previously Untreated Mantle Cell Lymphoma

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 30 Jan 2026

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At a glance

Drugs Acalabrutinib (Primary) ; Obinutuzumab (Primary) ; Venetoclax (Primary)
Indications Mantle-cell lymphoma
Focus Adverse reactions; Therapeutic Use
Acronyms MAVO

Most Recent Events

21 Jan 2026 Planned number of patients changed from 53 to 72.
21 Jan 2026 Planned End Date changed from 1 Jun 2026 to 31 Dec 2027.
21 Jan 2026 Planned primary completion date changed from 31 Dec 2025 to 30 Jun 2027.

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