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A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Sep 2026

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At a glance

  • Drugs Gefurulimab (Primary)
  • Indications Myasthenia gravis
  • Focus Registrational; Therapeutic Use
  • Acronyms PREVAIL
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 18 Sep 2026 Results presented in an AstraZeneca media release.
  • 18 Sep 2026 According to an AstraZeneca media release, based on results from this trial, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) based its positive opinion for Klygefa (gefurulimab) in treatment of adults with generalised myasthenia gravis (gMG).
  • 10 Apr 2026 Results presented in the Alexion, AstraZeneca Rare Disease Media Release

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