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A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 23 Apr 2026

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At a glance

  • Drugs Gefurulimab (Primary)
  • Indications Myasthenia gravis
  • Focus Registrational; Therapeutic Use
  • Acronyms PREVAIL
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 10 Apr 2026 Results presented in the Alexion, AstraZeneca Rare Disease Media Release
  • 10 Apr 2026 According to a Alexion, AstraZeneca Rare Disease media release, data from the trial will be presented at the American Academy of Neurology (AAN) Annual Meeting in Chicago, Illinois, 18 to 22 April 2026.
  • 06 Nov 2025 According to an AstraZeneca media release, based on results from this trial, the company has filed a regulatory application in Japan for Gefurulimab to treat generalized myasthenia gravis.

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