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A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel, Multicenter Study to Evaluate the Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 06 Jan 2026

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At a glance

  • Drugs Gefurulimab (Primary)
  • Indications Myasthenia gravis
  • Focus Registrational; Therapeutic Use
  • Acronyms PREVAIL
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 06 Nov 2025 According to an AstraZeneca media release, based on results from this trial, the company has filed a regulatory application in Japan for Gefurulimab to treat generalized myasthenia gravis.
  • 30 Oct 2025 Results presented in the Astrazeneca Media Release.
  • 29 Oct 2025 According toAlexion Pharmaceuticals media release, data from this trial will be presented at the American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM) Annual Meeting and the Myasthenia Gravis Foundation of America (MGFA) Scientific Session in San Francisco, California on October 29 to November 1, 2025.

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