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SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

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Trial Profile

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Clofutriben (Primary)
  • Indications Cushing syndrome
  • Focus Therapeutic Use
  • Acronyms RESCUE
  • Sponsors Sparrow Pharmaceuticals

    • Most Recent Events

    • 28 Oct 2024 According to a Sparrow Pharmaceuticals media release, company announced that the Phase 2 RESCUE trial of clofutriben, a potent and selective HSD-1 inhibitor, for the treatment of endogenous Cushings syndrome is complete. All eligible patients who completed the trial elected to continue treatment with clofutriben in an open label extension (OLE) protocol.
    • 28 Oct 2024 Status changed from active, no longer recruiting to completed, according to a Sparrow Pharmaceuticals media release.
    • 30 May 2024 According to a Sparrow Pharmaceuticals media release, interim data from ongoing clinical trials in patients with ACTH-dependent Cushing's syndrome will be presented by the David Katz during SY55 - Development of Novel Endocrine Therapies by Inhibiting Steroid Biosynthesis session.

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