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A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants With Active Psoriatic Arthritis Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

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Trial Profile

A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants With Active Psoriatic Arthritis Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 01 Oct 2026

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At a glance

  • Drugs Deucravacitinib (Primary)
  • Indications Plaque psoriasis; Psoriatic arthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms POETYK PsA-1
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 24 Sep 2026 Planned End Date changed from 10 Jun 2027 to 3 Jun 2027.
  • 17 Sep 2026 According to a Bristol-Myers Squibb media release, data from this study will be presented at an upcoming medical meeting.
  • 08 May 2026 According to a Bristol-Myers Squibb media release, the company announced that the European Commission has granted approval to Sotyktu (deucravacitinib), alone or in combination with methotrexate, for the treatment of active psoriatic arthritis (PsA) in adults who have had an inadequate response or who have been intolerant to a prior disease-modifying antirheumatic (DMARD) therapy. This EU approval is based on positive results from POETYK PsA-1 and POETYK PsA-2 trials.

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