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Phase I/Ib Study With the Combination of RMC-4630 (SHP2 Inhibitor) and LY3214996 (ERK Inhibitor) in Metastatic KRAS Mutant CRC, PDAC and NSCLC

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Trial Profile

Phase I/Ib Study With the Combination of RMC-4630 (SHP2 Inhibitor) and LY3214996 (ERK Inhibitor) in Metastatic KRAS Mutant CRC, PDAC and NSCLC

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Dec 2023

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At a glance

  • Drugs Temuterkib (Primary) ; Vociprotafib (Primary)
  • Indications Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms SHERPA

    • Most Recent Events

    • 24 Oct 2023 Results (n=11) presented at the 48th European Society for Medical Oncology Congress.
    • 01 Jun 2022 Status changed from not yet recruiting to recruiting.
    • 09 Mar 2022 Planned initiation date changed from 1 Feb 2022 to 1 Apr 2022.

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