Trial Profile

Phase I/Ib Study With the Combination of RMC-4630 (SHP2 Inhibitor) and LY3214996 (ERK Inhibitor) in Metastatic KRAS Mutant CRC, PDAC and NSCLC

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 29 Jan 2025

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At a glance

Drugs Temuterkib (Primary) ; Vociprotafib (Primary)
Indications Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer
Focus Adverse reactions; Therapeutic Use
Acronyms SHERPA

Most Recent Events

24 Jan 2025 Status changed from recruiting to discontinued (Reason the study was stopped: Due to a lack of safety and efficacy).
24 Oct 2023 Results (n=11) presented at the 48th European Society for Medical Oncology Congress.
01 Jun 2022 Status changed from not yet recruiting to recruiting.

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