A Phase II, Open-label, Multicentre, Randomised Study of Neoadjuvant and Adjuvant Treatment in Patients With Resectable, Early-stage (II to IIIB) Non-small Cell Lung Cancer (NeoCOAST-2)
Latest Information Update: 12 Aug 2026
At a glance
- Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Datopotamab deruxtecan (Primary) ; Durvalumab (Primary) ; Falbikitug (Primary) ; Monalizumab (Primary) ; Oleclumab (Primary) ; Paclitaxel (Primary) ; Pemetrexed (Primary) ; Rilvegostomig (Primary) ; Volrustomig (Primary) ; Infliximab; Mycophenolate mofetil
- Indications Non-small cell lung cancer
- Focus Adverse reactions; Therapeutic Use
- Acronyms NeoCOAST 2
- Sponsors AstraZeneca; AstraZeneca AB
Most Recent Events
- 06 Mar 2026 Planned End Date changed from 9 May 2030 to 28 May 2030.
- 06 Mar 2026 Planned primary completion date changed from 9 May 2030 to 28 May 2030.
- 01 Jun 2025 According to a Daiichi Sankyo Company Media Release, data from this study presented at the 2025 American Society of Clinical Oncology (#ASCO25) Annual Meeting and published in Nature Medicine.