A Phase 2, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses (15 mg and 30 mg QD) of CVL-231 (Emraclidine) in Participants With Schizophrenia Experiencing an Acute Exacerbation of Psychosis
Latest Information Update: 09 Apr 2025
At a glance
- Drugs Emraclidine (Primary)
- Indications Schizophrenia
- Focus Registrational; Therapeutic Use
- Acronyms EMPOWER-2
- Sponsors AbbVie; Cerevel Therapeutics
Most Recent Events
- 20 Dec 2024 Status changed from active, no longer recruiting to completed.
- 11 Nov 2024 Primary endpoint (Change from Baseline at Week 6 in the Positive and Negative Syndrome Scale (PANSS) total score [ Time Frame: Baseline through Week 6 ]) has not been met, according to results presented in the AbbVie media release.
- 11 Nov 2024 Results presented in the AbbVie media release.