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A Phase 2, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses (15 mg and 30 mg QD) of CVL-231 (Emraclidine) in Participants With Schizophrenia Experiencing an Acute Exacerbation of Psychosis

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A Phase 2, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses (15 mg and 30 mg QD) of CVL-231 (Emraclidine) in Participants With Schizophrenia Experiencing an Acute Exacerbation of Psychosis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 27 Dec 2024

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At a glance

  • Drugs Emraclidine (Primary)
  • Indications Schizophrenia
  • Focus Registrational; Therapeutic Use
  • Acronyms EMPOWER-2
  • Sponsors Cerevel Therapeutics

    • Most Recent Events

    • 20 Dec 2024 Status changed from active, no longer recruiting to completed.
    • 11 Nov 2024 Primary endpoint (Change from Baseline at Week 6 in the Positive and Negative Syndrome Scale (PANSS) total score [ Time Frame: Baseline through Week 6 ]) has not been met, according to results presented in the AbbVie media release.
    • 11 Nov 2024 Results presented in the AbbVie media release.

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