MC198B, Phase II Study of a Combination Therapy of Acalabrutinib, Venetoclax and Durvalumab in Patients With Richter Transformation From Chronic Lymphocytic Leukemia (CLL)
Latest Information Update: 26 Sep 2025
At a glance
- Drugs Acalabrutinib (Primary) ; Durvalumab (Primary) ; Venetoclax (Primary)
- Indications Chronic lymphocytic leukaemia
- Focus Therapeutic Use
- Sponsors Mayo Clinic
Most Recent Events
- 26 Aug 2025 Planned number of patients changed from 30 to 27.
- 26 Aug 2025 Planned End Date changed from 15 Jan 2027 to 22 Feb 2027.
- 26 Aug 2025 Planned primary completion date changed from 15 Jan 2027 to 22 Feb 2027.