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MC198B, Phase II Study of a Combination Therapy of Acalabrutinib, Venetoclax and Durvalumab in Patients With Richter Transformation From Chronic Lymphocytic Leukemia (CLL)

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Trial Profile

MC198B, Phase II Study of a Combination Therapy of Acalabrutinib, Venetoclax and Durvalumab in Patients With Richter Transformation From Chronic Lymphocytic Leukemia (CLL)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Apr 2025

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At a glance

  • Drugs Acalabrutinib (Primary) ; Durvalumab (Primary) ; Venetoclax (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Therapeutic Use
  • Sponsors Mayo Clinic

    • Most Recent Events

    • 20 Nov 2024 Planned End Date changed from 15 Nov 2025 to 15 Jan 2027.
    • 20 Nov 2024 Planned primary completion date changed from 15 Nov 2024 to 15 Jan 2027.
    • 25 Sep 2024 Planned number of patients changed from 33 to 30.

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