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A Non-interventional, Prospective, Open-label, Observational Study Evaluating the Effectiveness and Safety of Acalabrutinib (Calquence®) in Patients With Chronic Lymphocytic Leukemia (CLL) Receiving Direct Oral Anticoagulation (DOAC).

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Trial Profile

A Non-interventional, Prospective, Open-label, Observational Study Evaluating the Effectiveness and Safety of Acalabrutinib (Calquence®) in Patients With Chronic Lymphocytic Leukemia (CLL) Receiving Direct Oral Anticoagulation (DOAC).

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 13 May 2026

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At a glance

  • Drugs Acalabrutinib (Primary) ; Obinutuzumab (Primary)
  • Indications Chronic lymphocytic leukaemia
  • Focus Adverse reactions
  • Acronyms CICERO

Most Recent Events

  • 01 May 2026 Status changed from active, no longer recruiting to completed.
  • 30 Apr 2025 Status changed from recruiting to active, no longer recruiting.
  • 17 Jan 2025 The protocol has been amended to increase in study time frame.

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