Trial Profile

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease: MARINER

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 08 Oct 2025

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At a glance

Drugs Dupilumab (Primary)
Indications Aspirin-induced asthma; Nasal polyps; Rhinosinusitis
Focus Pharmacodynamics
Acronyms MARINER

Most Recent Events

16 Sep 2025 "Chronic rhinosinusitis" is added to indications.
16 Sep 2025 Status changed from recruiting to active, no longer recruiting.
27 Feb 2024 Planned End Date changed from 1 Nov 2027 to 30 Apr 2026.

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