Trial Profile

Combined Hepatic Arterial Infusion Chemotherapy, Tyrosine Kinase Inhibitor/ Anti-VEGF Antibody, and Anti-PD-1/ PD-L1 Antibody As Conversion Therapy for Unresectable Hepatocellular Carcinoma

Status: Recruiting

Phase of Trial: Phase IV

Latest Information Update: 28 Mar 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Bevacizumab (Primary) ; Camrelizumab (Primary) ; Donafenib (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Lenvatinib (Primary) ; Nivolumab (Primary) ; Oxaliplatin (Primary) ; Pembrolizumab (Primary) ; Regorafenib (Primary) ; Rivoceranib (Primary) ; Sintilimab (Primary) ; Sorafenib (Primary) ; Tislelizumab (Primary) ; Toripalimab (Primary)
Indications Liver cancer
Focus Therapeutic Use
Acronyms HAIC-TKI-ICI

25 Mar 2025 Planned End Date changed from 30 Dec 2024 to 30 Dec 2025.
25 Mar 2025 Planned primary completion date changed from 30 Apr 2024 to 30 Jun 2025.
01 Jun 2023 Planned primary completion date changed from 30 Apr 2023 to 30 Apr 2024.

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