Trial Profile

A Prospective Multicenter Phase 2 Study of the Chemotherapy-light Combination of Intravenous Rituximab With the Antibody-drug Conjugate Polatuzumab Vedotin and the Bispecific Antibody Glofitamab in Previously Untreated Aggressive B-cell Lymphoma Patients Above 60 Years of Age Ineligible for a Fully Dosed R-CHOP

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 12 May 2025

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At a glance

Drugs Glofitamab (Primary) ; Obinutuzumab (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary)
Indications B-cell lymphoma; Diffuse large B cell lymphoma
Focus Therapeutic Use
Acronyms R-Pola-Glo

02 May 2025 Status changed from recruiting to active, no longer recruiting.
08 Nov 2024 Planned number of patients changed from 80 to 125.
08 Nov 2024 Planned primary completion date changed from 30 Sep 2027 to 30 Apr 2025.

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