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A Phase 1b/2 Study of Glutamine Antagonist DRP-104 in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Hepatocellular Carcinoma (FLC)

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Trial Profile

A Phase 1b/2 Study of Glutamine Antagonist DRP-104 in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Hepatocellular Carcinoma (FLC)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 26 Feb 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Sirpiglenastat (Primary)
  • Indications Liver cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 21 Feb 2025 Planned End Date changed from 1 Aug 2029 to 1 Sep 2033.
    • 21 Feb 2025 Planned primary completion date changed from 1 Feb 2027 to 1 Sep 2028.
    • 04 Nov 2024 Planned End Date changed from 1 Feb 2027 to 1 Aug 2029.

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