Trial Profile

Phase 1 Trial of MK-2870 as Monotherapy and in Combination With Pembrolizumab ± Chemotherapy in Subjects With Advanced Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 25 Dec 2025

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At a glance

Drugs Pembrolizumab (Primary) ; Sacituzumab tirumotecan (Primary) ; Carboplatin
Indications Non-small cell lung cancer; Solid tumours
Focus Adverse reactions
Acronyms TroFuse-008
Sponsors Merck Sharp & Dohme

Most Recent Events

19 Dec 2025 Status changed from recruiting to active, no longer recruiting.
21 Aug 2025 Status changed from active, no longer recruiting to recruiting.
14 Aug 2025 Planned number of patients changed from 36 to 30.

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