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A Drug-Drug Interaction Study to Assess the Effect of Orforglipron on the Pharmacokinetics of Digoxin, Simvastatin, Rosuvastatin, Acetaminophen, and Midazolam in Healthy Overweight and Obese Participants

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Trial Profile

A Drug-Drug Interaction Study to Assess the Effect of Orforglipron on the Pharmacokinetics of Digoxin, Simvastatin, Rosuvastatin, Acetaminophen, and Midazolam in Healthy Overweight and Obese Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Jul 2024

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At a glance

  • Drugs Orforglipron (Primary) ; Digoxin; Midazolam; Paracetamol; Rosuvastatin; Simvastatin; Sodium bicarbonate
  • Indications Obesity; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Eli Lilly and Company

    • Most Recent Events

    • 22 Jul 2024 Status changed from active, no longer recruiting to completed.
    • 28 May 2024 Planned End Date changed from 1 Jun 2024 to 17 Jun 2024.
    • 28 May 2024 Planned primary completion date changed from 1 Jun 2024 to 17 Jun 2024.

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