Trial Profile

Phase II Study Evaluating the Addition of Elacestrant, an Oral Selective Estrogen Receptor Degrader (SERD), to Standard-of-care Olaparib in Patients With Hormone Receptor (HR)-Positive, HER2-negative Locally Advanced or Metastatic Breast Cancer With gBRCA1/2 Mutations

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 30 Sep 2025

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At a glance

Drugs Elacestrant (Primary) ; Niraparib (Primary) ; Olaparib (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
Focus Therapeutic Use
Acronyms ELEMENT

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