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A phase 1b single-arm, open-label, study of emavusertib (CA-4948) in combination with azacitidine and venetoclax in acute myeloid leukemia patients in complete response with measurable residual disease

Trial Profile

A phase 1b single-arm, open-label, study of emavusertib (CA-4948) in combination with azacitidine and venetoclax in acute myeloid leukemia patients in complete response with measurable residual disease

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Apr 2025

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At a glance

  • Drugs Emavusertib (Primary) ; Azacitidine; Venetoclax
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions

Most Recent Events

  • 31 Mar 2025 According to a Curis media release, results of this trial were published in a financial report.
  • 31 Mar 2025 According to a Curis media release, company initiated the study and first dosing cohort was completed and well tolerated, with no unexpected adverse events. The external Clinical Safety Review Committee recommended escalation to the next dosing cohort. Enrollment for this cohort is currently ongoing.
  • 18 Jun 2024 New trial record

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