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A Phase 1/2 Open-label Clinical Study to Evaluate the Safety and Efficacy of Intravesical Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in Participants With Intermediate-risk Non-muscle Invasive Bladder Cancer (NMIBC)

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Trial Profile

A Phase 1/2 Open-label Clinical Study to Evaluate the Safety and Efficacy of Intravesical Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in Participants With Intermediate-risk Non-muscle Invasive Bladder Cancer (NMIBC)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 01 Jul 2025

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At a glance

  • Drugs Sacituzumab Tirumotecan (Primary)
  • Indications Bladder cancer
  • Focus Adverse reactions
  • Acronyms TroFuse-027
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 03 Apr 2025 Planned End Date changed from 30 Nov 2026 to 31 Jul 2028.
  • 09 Jan 2025 Status changed from not yet recruiting to recruiting.
  • 12 Nov 2024 Planned initiation date changed from 27 Nov 2024 to 26 Dec 2024.

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