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A Phase 2 Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of WIN378 in Participants With Moderate - Severe Chronic Obstructive Pulmonary Disease

Trial Profile

A Phase 2 Randomized, Double-blind, Placebo-controlled, Dose-ranging Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of WIN378 in Participants With Moderate - Severe Chronic Obstructive Pulmonary Disease

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 26 Oct 2026

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At a glance

  • Drugs HBM 9378 (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Adverse reactions; Pharmacokinetics
  • Acronyms SIRIUS
  • Sponsors Windward Bio

Most Recent Events

  • 09 Jun 2026 According to Harbour BioMed media release, first patient has been dosed.
  • 09 Jun 2026 According to Sichuan Kelun-Biotech Biopharmaceutical media release, company announced that the first patients have been dosed in the Phase 2 SIRIUS study of WIN378, the companys ultra long-acting anti-TSLP monoclonal antibody, in patients with chronic obstructive pulmonary disease (COPD).
  • 04 May 2026 According to Windward Bio media release, the trial is anticipated to start in the second quarter of 2026.

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