Trial Profile

A Phase 3 Randomized, Open-label, Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 08 Mar 2026

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At a glance

Drugs Pembrolizumab (Primary) ; Sacituzumab Tirumotecan (Primary) ; Carboplatin; Docetaxel; Paclitaxel
Indications Carcinoma; Endometrial cancer
Focus Therapeutic Use
Acronyms TroFuse033
Sponsors Merck Sharp & Dohme

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