A Prospective, Single-arm Phase II Trial of Trilaciclib Administered Prior to Sacituzumab Tirumotecan in Patients With EGFR-mutated, Advanced Non-Small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors
Latest Information Update: 17 Apr 2026
At a glance
- Drugs Sacituzumab tirumotecan (Primary) ; Trilaciclib (Primary)
- Indications Non-small cell lung cancer
- Focus Adverse reactions
- Acronyms PROTECT-2
Most Recent Events
- 14 Apr 2026 Planned End Date changed from 1 May 2027 to 1 Dec 2027.
- 14 Apr 2026 Planned primary completion date changed from 1 Jun 2026 to 1 Mar 2027.
- 14 Apr 2026 Status changed from not yet recruiting to recruiting.