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A Randomized, Open-label, Multicenter Phase III Clinical Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2-negative (HER2-) Breast Cancer Who Have Previously Failed Endocrine Therapy

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Trial Profile

A Randomized, Open-label, Multicenter Phase III Clinical Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic Hormone Receptor-positive (HR+)/Human Epidermal Growth Factor Receptor 2-negative (HER2-) Breast Cancer Who Have Previously Failed Endocrine Therapy

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 04 Sep 2025

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At a glance

  • Drugs Sacituzumab Tirumotecan (Primary) ; Capecitabine; Paclitaxel
  • Indications HER2 negative breast cancer; Male breast cancer
  • Focus Therapeutic Use
  • Sponsors Sichuan Kelun-Biotech Biopharmaceutical

Most Recent Events

  • 14 Aug 2025 Status changed from not yet recruiting to recruiting.
  • 31 Jul 2025 New trial record

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