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A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes

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Trial Profile

A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 19 Sep 2025

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At a glance

  • Drugs Retatrutide (Primary) ; Tirzepatide
  • Indications Non-alcoholic fatty liver disease
  • Focus Registrational; Therapeutic Use
  • Acronyms SYNERGY-OUTCOMES
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 19 Sep 2025 New trial record

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