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A Prospective, Single-arm, Phase 4 Study to Evaluate the Course of Serum Transthyretin (TTR) Level With Acoramidis in Adult Patients With Variant or Wild-type Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) Previously Treated With Tafamidis

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Trial Profile

A Prospective, Single-arm, Phase 4 Study to Evaluate the Course of Serum Transthyretin (TTR) Level With Acoramidis in Adult Patients With Variant or Wild-type Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) Previously Treated With Tafamidis

Status: Not yet recruiting
Phase of Trial: Phase IV

Latest Information Update: 16 Feb 2026

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At a glance

  • Drugs Acoramidis (Primary)
  • Indications Cardiomyopathies
  • Focus Therapeutic Use
  • Acronyms ACO-SWITCH
  • Sponsors Bayer

Most Recent Events

  • 11 Feb 2026 Planned initiation date changed from 25 Jan 2026 to 13 Feb 2026.
  • 09 Jan 2026 Planned initiation date changed from 22 Dec 2025 to 25 Jan 2026.
  • 29 Dec 2025 New trial record

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